Joseph R. Sachleben, Ph. D.
Assistant
Professor
Chemistry
Department
Otterbein
College
Phone:
(614) 823-1666
Fax:
(614) 823-1968
Email: jsachleben@otterbein.edu
Ph.D. in Physical Chemistry, University of
California, Berkeley (December 1993)
Research
Advisor: A. Pines
Thesis Title: "Nuclear Magnetic Relaxation
Studies of Semiconductor Nanocrystals and Solids"
S.M. in Biochemistry, University of Chicago
(June1988)
Research
Advisor: M. Makinen
Thesis Title: "Determining Molecular
Conformation by ENDOR spectroscopy and Molecular Modeling."
A.B. in Chemistry, The University of Chicago (June 1988)
Chemistry140, 150, 160 Ð General Chemistry
Chemistry280 Ð Analytical Chemistry
Chemistry330 Ð Biophysical Chemistry
Chemistry340, 350 Ð Physical Chemistry
Chemistry380 Ð Instrumental Chemistry
Chemistry400 Ð Chemistry Seminar
Chemistry465 Ð Advanced Biochemistry
INST340 Ð Chemistry and Our Lives
I have been probing the interactions between soils and pollutants by solid-state NMR spectroscopy. These studies directly probe the interaction between pollutants and organic soil constituents and are directly relevant towards understanding the bioavailability and possible remediation methods of pollution.
I am also interested in the fundamental aspects of
solid-state NMR spectroscopy. These interests currently fall into three
separate programs: developing a theoretical understanding of heteronuclear
decoupling under fast magic angle spinning (MAS), understanding the effects of
paramagnetic lanthanide metals on the solid-state NMR spectrum, and utilizing
Bayesian statistics to analyze solid-state NMR spectra.
1.
D. Mustafi, J.Sachleben,
G. Wells, M. Makinen. "Structure and Conformation of Spin-Labeled Amino
Acids in Frozen Solutions Determined by Electron Nuclear Double Resonance. 1.
MethylN-(2,2,5,5-Tetramethyl-1-oxypyrrolinyl-3-carbonyl)-L-alanate, a Molecule
with a Single Preferred Conformation" J. Am.Chem. Soc. 112 (1990)
2558.
2.
A. Llor, Z. Olejniczak, J. Sachleben,
and A. Pines. "Scaling and Time Reversal of Spin Couplings in Zero-Field
NMR." Phys. Rev. Lett. 67 (1991) 1989.
3.
J.R. Sachleben, E.W. Wooten, L. Emsley, A. Pines, V.
Colvin,and A.P. Alivisatos.
"NMR Studies of the Surface Structure and Dynamics of Semiconductor
Nanocrystals." Chem. Phys. Lett. 198 (1992) 431.
4.
M. Goldman,
P.Grandinetti, A. Llor, Z. Olejniczak, J. Sachleben. J. Zwanziger.
"Theoretical Aspects of Higher Order Truncations." J.Chem. Phys. 97 (1992) 8947.
5.
Joseph R.
Sachleben, Stefano Caldarelli, and
Lyndon Emsley. "The Effect of Spin Decoupling on Lineshapes in
Solid-StateNuclear Magnetic Resonance." J. Chem. Phys. 104 (1996)
2518.
6.
Ales Medek, Joseph
R. Sachleben, Peter Beverwyk, and Lucio Frydman. "Multi-Rank NMR
Studies of Half-Integer Quadrupoles in Solids by Dynamic-Angle Correlation
Spectroscopy." J. Chem. Phys. 104. (1996) 5374.
7.
J.R. Sachleben, V. Frydman, L. Frydman. "Dipolar
Determinations in Solids using Relaxation-Assisted NMR Recoupling." J.Am.
Chem. Soc. 118. (1996) 9786.
8.
Joseph R. Sachleben, Lucio Frydman. "Orientational Alignment in
Solids from Bidimensional Isotropic-Anisotropic NMR spectroscopy: Applications
to the analysis of Aramide Fibers." Solid-State NMR. 7 (1997) 301.
9.
J.R. Sachleben, V.L. Colvin, L. Emsley, E.W. Wooten, and A.P.
Alivisatos. "Solution State NMR Studies of the Structure and
SurfaceDynamics of
SemiconductorNanocrystals." Journal of Physical Chemistry B. 102
(1998) 10117.
10.
Susan E. Latturner,
Joseph Sachleben, Bo B. Iversen, Jonathan Hanson, and Galen D.Stucky. "Covalent
Guest-Framework Interactions in Heavy Metal Sodalites: Structure and Properties
of Thallium and Silver Sodalite." Journal ofPhysical Chemistry B. 103
(1999) 7135.
11.
A.T. Chien, X.Xu,
J.H. Kim, J. Sachleben, J.S. Speck, and F.F. Lange. "Electrical
Characterization of BaTiO3 Heteroepitaxial Thin Films by
Hydrothermal Synthesis" Journal of Materials Research. 14 (1999) 3330.
12. A.T. Chien, J.Sachleben, J.H. Kim, J.S. Speck,
and F.F. Lange. "Synthesis and Characterization of PbTiO3 Powders
and Heteroepitaxial Thin Films by Hydrothermal Synthesis." Journal of
Materials Research. 14 (1999) 3303.
13. Joseph R. Sachleben, Peter Beverwyk, Lucio Frydman." Multidimensional Dipolar Exchange-Assisted Recoupling Measurements in Solid-State NMR" Journal of Magnetic Resonance. 144 (2000) 330.
14. H.-T. Kwak, S. Prasad, Z. Yao, P.J. Grandinetti, J.R. Sachleben, L. Emsley. ÒEnhanced Sensitivity in RIACT/MQ-MAS NMR Experiments Using Rotor Assisted Polarization Transfer.Ó Journal of Magnetic Resonance. 150 (2001) 71.
15. K. Dria, J.R. Sachleben, P.G. Hatcher.
ÒSolid-State 13C NMR of Humic Acids at High Magnetic Field
Strengths: The Case for High Spinning Frequencies and Advanced
Cross-Polarization and Decoupling Techniques.Ó Journal of Environmental
Quality. 31(2002) 393.
16. Y. Vodovotz, E. Vittadini, J.R. Sachleben.
ÒUse of 1H Nuclear Magnetic Cross Relaxation Spectroscopy to Probe the Changes
in Bread and its Components upon Aging.Ó Carbohydrate Research, 337
(2002) 147.
17. Michael A. Coutant, Joseph R. Sachleben,
Prabir K.Dutta. ÒEffect of Rotational Mobility on Photoelectron Transfer:
Comparison of Two Zeolite Topologies.Ó Journal of Physical Chemistry B. 107 (2003)
11,000.
18. Joseph R. Sachleben, Benny Chefetz, Ashish Deshmukh, Patrick G. Hatcher. ÒSolid-State NMR
Characterization of Pyrene-Cuticular Matter Interactions.Ó Environmental
Science and Technology. 38 (2004) 4369.