Nucleic Acids - Nucleosides and Nucleotides

Nucleosides

The combination of a base and a sugar is called a nucleoside. Two examples are shown below.

guanine + ribose =
guanosine

cytosine + deoxyribose =
deoxycytidine

 

Nucleotides

Nucleotides are comprised of three portions, a base, a sugar, and a phosphate. Addition of a phosphate group at the 5' (or 3') position of the sugar turns the nucleoside into a nucelotide. A familiar example, adenosine monophosphate or AMP, is shown below


adenine + ribose + phosphate = adenosine 5'-monophosphate (AMP)

 

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